Description

5-Pyrimidineacetic Acid, 1,2,3,4-Tetrahydro-2,4-Dioxo-1-β-D-Ribofur Anosyl-, Methyl Ester is a specialized nucleoside derivative, a key intermediate in the synthesis of modified nucleic acids and antiviral compounds. Its precise chemical structure makes it a critical building block for pharmaceutical research and development, particularly in the creation of novel therapeutics. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a modified nucleoside building block for studying enzyme mechanisms and nucleic acid interactions.
• Antiviral Drug Development: Serves as a key scaffold in the research and production of experimental antiviral agents targeting viral polymerases.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of high-value, complex organic molecules for specialized applications.
• Proteomics & Genomics: Utilized in the development of probes and tools for molecular biology and diagnostic assay development.

Basic Information

Product Name	5-Pyrimidineacetic Acid, 1,2,3,4-Tetrahydro-2,4-Dioxo-1-β-D-Ribofur Anosyl-, Methyl Ester
CAS No.	29428-50-0
Molecular Formula	C₁₂H₁₄N₂O₈
Molecular Weight	314.25 g/mol
Synonyms	1-(β-D-Ribofuranosyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-acetic acid methyl ester; Methyl 1-(β-D-ribofuranosyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-acetate; 5-Carboxymethyl-1-β-D-ribofuranosyluracil methyl ester; 1-β-D-Ribofuranosyl-5-pyrimidineacetic acid, 1,2,3,4-tetrahydro-2,4-dioxo-, methyl ester; Methyl 1-β-D-ribofuranosyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-acetate
EINECS	Contact for details

Quality Control

Our 5-Pyrimidineacetic Acid, 1,2,3,4-Tetrahydro-2,4-Dioxo-1-β-D-Ribofur Anosyl-, Methyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including research-grade and GMP-starting material specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.