Description

6-Selenoguanosine is a selenium-containing nucleoside analog of guanosine, where the oxygen atom in the carbonyl group is replaced by selenium. This structural modification makes it a valuable biochemical tool for studying nucleic acid structure, function, and redox chemistry. It is primarily utilized in advanced life science research and pharmaceutical development. Key industries requiring this specialized compound include academic and industrial research laboratories focused on biochemistry, molecular biology, and medicinal chemistry.

Application

• Biochemical Research: Used as a probe to study the structure, dynamics, and catalytic mechanisms of nucleic acids, particularly tRNA and ribozymes.
• Medicinal Chemistry: Serves as a key intermediate or precursor in the synthesis of novel nucleoside analogs with potential therapeutic applications.
• Antioxidant Studies: Investigated for its role in selenium metabolism and as a model compound to understand selenium's antioxidant properties within biological systems.
• X-ray Crystallography: The selenium atom acts as a heavy atom marker for phase determination in the structural analysis of oligonucleotides.
• Enzyme Substrate Studies: Employed as a substrate or inhibitor for enzymes that interact with guanosine, such as nucleoside phosphorylases and kinases.
• Spectroscopic Probes: Utilized in UV-Vis and fluorescence spectroscopy due to the distinct photophysical properties imparted by the selenium atom.

Basic Information

Product Name	6-Selenoguanosine
CAS No.	29411-74-3
Molecular Formula	C10H13N5O4Se
Molecular Weight	346.21 g/mol
Synonyms	6-Selenoguanosine; Guanosine, 6-seleno-; 6-Se-Guo; 2-Amino-6-seleno-9-β-D-ribofuranosylpurine; 6-Seleno-guanosine; 6-Seleno-9-β-D-ribofuranosylguanine; Selenoguanosine; 6-SeG
EINECS	Contact for details

Quality Control

Our 6-Selenoguanosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and elemental analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the exact specifications and test results. Our commitment ensures the material meets the high standards required for sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.