Description

Ciclopirox CAS NO 29342-05-0 is a broad-spectrum synthetic antifungal agent belonging to the hydroxypyridone class. It is valued for its unique mechanism of action, which involves chelation of polyvalent metal ions, leading to the inhibition of metal-dependent enzymes crucial for fungal cell function. This compound is essential for manufacturers in the pharmaceutical and personal care industries, serving as the active pharmaceutical ingredient (API) in topical formulations for treating fungal skin and nail infections, as well as in antidandruff shampoos.

Application

• Primary Active Pharmaceutical Ingredient (API) in topical antifungal creams, ointments, and solutions for athlete's foot, ringworm, and cutaneous candidiasis.
• Key component in medicated nail lacquers and treatments for onychomycosis (fungal nail infections).
• Formulation base for antidandruff shampoos and scalp treatments, targeting Malassezia fungi.
• Incorporation into veterinary topical products for fungal infections in animals.
• Use in preservative systems for cosmetic and personal care products to prevent microbial spoilage.
• Research and development of novel drug delivery systems to enhance bioavailability.

Basic Information

Product Name	Ciclopirox
CAS No.	29342-05-0
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone; Ciclopirox Olamine (salt form); HOE 296b; Loprox; Batrafen; Brumixol; Ciclopirox ethanolamine; CPX; Hydroxypyridone antifungal
EINECS	249-552-0

Quality Control

Our Ciclopirox is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with typical specifications aligning with pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Enumeration	Meets Ph. Eur./USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.