Description

Metipirox is a synthetic antifungal agent with a unique chemical structure, offering a broad spectrum of activity against dermatophytes and yeasts. Its primary value lies in its fungistatic and fungicidal properties, making it a critical active ingredient for formulations targeting superficial fungal infections. This compound is essential for manufacturers in the pharmaceutical and personal care industries, particularly for developing topical antifungal creams, powders, and medicated shampoos.

Application

• Topical Antifungal Pharmaceuticals: Primary active ingredient in creams, ointments, gels, and solutions for treating athlete's foot (tinea pedis), ringworm, and other cutaneous mycoses.
• Medicated Personal Care: Key component in antifungal powders, sprays, and medicated shampoos designed for dandruff control and scalp health.
• Veterinary Dermatology: Used in topical preparations for treating fungal skin infections in companion animals.
• Preservative Systems: Can be employed as a fungicidal preservative in specific cosmetic and topical product formulations to prevent microbial spoilage.
• Research & Development: Serves as a reference standard and active pharmaceutical ingredient (API) in pharmaceutical R&D for novel antifungal therapies.

Basic Information

Product Name	Metipirox
CAS No.	29342-02-7
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone; HOE 296; Piroctone Olamine (as the ethanolamine salt); Octopirox; Piroctone Ethanolamine; 1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone (common mis-assignment, correct for Piroctone); 6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one
EINECS	249-558-4

Quality Control

Our Metipirox is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. Quality is verified through a comprehensive suite of analytical tests including HPLC for assay and impurity profiling, IR for identification, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.