Description

α-(Trimethylsiloxy)Benzeneacetic Acid Methyl Ester is a versatile organosilicon intermediate with significant utility in advanced organic synthesis. Its value lies in its dual functionality, serving as a protected form of mandelic acid and a silyl enol ether precursor, enabling complex transformations under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the development of active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral drugs, anti-inflammatory agents, and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific stereochemistry.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, including asymmetric synthesis.
• Polymer Modification: Can be utilized to introduce siloxy and ester functionalities into polymer backbones for material science applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions.

Basic Information

Product Name	α-(Trimethylsiloxy)Benzeneacetic Acid Methyl Ester
CAS No.	29233-93-0
Molecular Formula	C₁₂H₁₈O₃Si
Molecular Weight	238.36 g/mol
Synonyms	Methyl 2-(trimethylsiloxy)-2-phenylacetate; Methyl α-(trimethylsiloxy)phenylacetate; Methyl (trimethylsiloxy)(phenyl)acetate; Mandelic acid methyl ester trimethylsilyl ether; 2-(Trimethylsiloxy)-2-phenylacetic acid methyl ester; Phenylglyoxylic acid methyl ester O-trimethylsilyl enol ether; (Trimethylsiloxy)(phenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our α-(Trimethylsiloxy)Benzeneacetic Acid Methyl Ester is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.