Description

5-tert-Butyl-Thiophene-2-Carbonyl Chloride is a high-purity, reactive organic intermediate essential for advanced chemical synthesis. This compound matters as a key building block for introducing the tert-butyl-thiophene moiety into more complex molecular architectures, enabling the development of novel materials and active compounds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the tert-butyl-thiophene group confers specific biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal-organic catalysis and coordination chemistry applications.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.

Basic Information

Product Name	5-tert-Butyl-Thiophene-2-Carbonyl Chloride
CAS No.	29212-25-7
Molecular Formula	C9H11ClOS
Molecular Weight	202.70 g/mol
Synonyms	5-tert-Butyl-2-thiophenecarbonyl chloride; 5-(tert-Butyl)thiophene-2-carbonyl chloride; 2-Thiophenecarbonyl chloride, 5-(1,1-dimethylethyl)-; 5-tert-Butylthiophene-2-carboxylic acid chloride; 5-(tert-Butyl)thiophene-2-carboxylic acid chloride; 2-Carbonyl chloride-5-tert-butylthiophene; 5-tert-Butyl-2-thiophenecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-Thiophene-2-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.