Description

Phenylisopropyladenosine is a potent and selective adenosine A1 receptor agonist. This high-purity biochemical is critical for research and development in pharmacology and neuroscience, serving as a key tool compound for studying adenosine receptor signaling pathways. It is essential for scientists and manufacturers in the pharmaceutical, biotechnology, and academic research sectors who require reliable, high-quality intermediates for drug discovery and biochemical assays.

Application

• Pharmacological Research: A standard reference agonist for studying adenosine A1 receptor function, signaling, and desensitization in vitro and in vivo.
• Drug Discovery & Development: Used as a critical intermediate or reference standard in the synthesis and screening of novel cardiovascular and neurological therapeutics.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays and receptor binding studies.
• Neuroscience Studies: A key tool for investigating the role of adenosine receptors in neuroprotection, sleep regulation, and pain pathways.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in cellular physiology and molecular pharmacology.
• GMP Intermediate Production: Available in controlled grades suitable for use as a starting material or intermediate in cGMP-compliant pharmaceutical manufacturing processes.

Basic Information

Product Name	Phenylisopropyladenosine
CAS No.	29193-86-0
Molecular Formula	C15H17N5O4
Molecular Weight	331.33 g/mol
Synonyms	PIA; N6-(2-Phenylisopropyl)adenosine; R(-)-N6-(2-Phenyl-1-methylethyl)adenosine; (R)-(-)-N6-(1-Methyl-2-phenylethyl)adenosine; (R)-PIA; N6-(1-Methyl-2-phenylethyl)adenosine; L-PIA; Adenosine, N6-(2-phenyl-1-methylethyl)-, (R)-
EINECS	Contact for details

Quality Control

Our Phenylisopropyladenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification and impurity profiling. Certificates of Analysis (COA) with full traceability are provided, ensuring compliance with research and development standards. Custom synthesis and purification to meet specific project requirements, including cGMP guidelines for advanced applications, are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.