Description

2',3'-Di-o-Acetyl-D-Uridine is a key acetylated derivative of the nucleoside uridine, widely utilized as a crucial building block in organic synthesis and pharmaceutical research. This compound is essential for the protection of ribose hydroxyl groups, enabling the controlled synthesis of complex nucleoside analogs and oligonucleotides. It serves as a vital intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent industries, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside drugs.
• Oligonucleotide Synthesis: Used as a protected monomer for the solid-phase synthesis of RNA and modified oligonucleotides.
• Biochemical Research: Serves as a substrate or intermediate in enzymatic studies and metabolic pathway investigations.
• Prodrug Development: Employed in the design of prodrugs to enhance the bioavailability and stability of therapeutic nucleosides.
• Diagnostic Reagent Manufacturing: Used in the production of labeled probes and other diagnostic components.
• Academic & Industrial R&D: A fundamental reagent for chemical biology and medicinal chemistry research programs.

Basic Information

Product Name	2',3'-Di-o-Acetyl-D-Uridine
CAS No.	29108-90-5
Molecular Formula	C13H16N2O8
Molecular Weight	328.27 g/mol
Synonyms	2',3'-Di-O-acetyluridine; 1-[(2R,3R,4R,5R)-3,4-Diacetoxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; Uridine, 2',3'-diacetate; D-Uridine, 2',3'-diacetate; 2',3'-Diacetyluridine; 2',3'-O-Diacetyluridine; 2',3'-Di-O-acetyl-D-uridine; 2',3'-Diacetyl-D-uridine
EINECS	Contact for details

Quality Control

Our 2',3'-Di-o-Acetyl-D-Uridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and production applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.