Description

17-Hydroxypregnenolone Sulfate is a key sulfated steroid metabolite and a crucial biochemical intermediate in the biosynthesis of steroid hormones. This compound is essential for research and development in endocrinology, providing insights into steroidogenic pathways and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, diagnostic manufacturers, and academic institutions focused on hormone research, metabolic studies, and the development of analytical standards.

Application

• Biochemical Research: Used as a critical intermediate and reference standard in studying steroidogenesis, particularly the pathways leading to DHEA, cortisol, and sex hormones.
• Diagnostic Development: Serves as a calibrator or control material in the development of immunoassays and LC-MS/MS methods for clinical diagnostics related to adrenal function and congenital adrenal hyperplasia (CAH).
• Pharmaceutical Reference Standard: Employed as a high-purity chemical reference standard (CRS) for quality control and analytical method validation in drug development.
• Metabolic Pathway Analysis: A vital tool for investigating sulfotransferase and sulfatase enzyme activities and understanding steroid metabolism in various disease models.
• Academic & Clinical Studies: Facilitates research into endocrine disorders, prenatal screening, and the biochemical basis of steroid-related conditions.

Basic Information

Product Name	17-Hydroxypregnenolone Sulfate
CAS No.	28901-70-4
Molecular Formula	C21H32O6S
Molecular Weight	412.54 g/mol
Synonyms	3β,17α-Dihydroxypregn-5-en-20-one 3-sulfate; Pregnenolone, 17-hydroxy-, sulfate; 17α-Hydroxypregnenolone 3-sulfate; 17-OH-Pregnenolone Sulfate; 17α-Hydroxypregnenolone sulfate; (3β,17α)-17-Hydroxypregn-5-en-20-one 3-(Hydrogen Sulfate)
EINECS	Contact for details

Quality Control

Our 17-Hydroxypregnenolone Sulfate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods (NMR, MS), to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.