Description

Carbonochloridic Acid (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl Ester is a specialized chlorocarbonate derivative, primarily serving as a key chiral building block and protecting group reagent in advanced organic synthesis. Its value lies in enabling the controlled introduction of functional groups and facilitating stereoselective reactions critical for producing complex molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for API synthesis and process development.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and antivirals.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where specific chirality is required for biological activity.
• Peptide Chemistry: Acts as a protecting group reagent for hydroxyl functions during the synthesis of complex peptides and glycopeptides.
• Carbohydrate Chemistry: Employed in the modification and protection of sugar derivatives for the synthesis of nucleosides and other bioactive carbohydrate-based molecules.
• Asymmetric Synthesis: Serves as a reagent in catalytic asymmetric transformations to construct chiral centers with high enantiomeric excess.
• Polymer Science: Used in the research and development of specialty polymers and functional materials requiring specific chiral monomers.

Basic Information

Product Name	Carbonochloridic Acid (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl Ester
CAS No.	28863-62-9
Molecular Formula	C7H11ClO4
Molecular Weight	194.62 g/mol
Synonyms	(4R-cis)-4-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol Chloroformate; (4R-cis)-4-(Hydroxymethyl)-2,2-Dimethyl-1,3-Dioxolane-4-Methanol Chloroformate; (4-Chloromethyl-2,2-dimethyl-1,3-dioxolan-4-yl)methyl Chloroformate; 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-(chloromethyl)-, Chloroformate; Solketal Chloroformate; (R)-(-)-4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane-4-methanol Chloroformate; (R)-Solketal Chloroformate
EINECS	Contact for details

Quality Control

Our Carbonochloridic Acid (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance as a synthesis reagent. We provide comprehensive Certificates of Analysis (COA) detailing purity, assay, enantiomeric excess, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Density	~1.25 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.