Description

Bicyclo[6.1.0]Non-2-Ene-9-Carbonyl Chloride (8Ci,9Ci) is a highly reactive strained bicyclic acid chloride derivative, serving as a critical building block for advanced organic synthesis. Its unique fused ring structure and reactive carbonyl chloride group make it invaluable for introducing complex, rigid molecular frameworks into target compounds. This specialty intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those requiring strained ring systems for biological activity or conformational restriction.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection, where the bicyclic scaffold can contribute to unique modes of action.
• Material Science Research: Building block for creating novel polymers, dendrimers, or liquid crystals with specific mechanical or optical properties derived from its rigid geometry.
• Cross-Coupling Reactions: Serves as an electrophile in various metal-catalyzed coupling reactions to form carbon-carbon bonds for complex molecule assembly.
• Ligand and Catalyst Development: Intermediate for synthesizing specialized chelating ligands or organocatalysts used in asymmetric synthesis.
• Peptide Mimetics and Conjugation: Facilitates the introduction of hydrophobic, constrained structures into peptide chains or for bioconjugation strategies.

Basic Information

Product Name	Bicyclo[6.1.0]Non-2-Ene-9-Carbonyl Chloride (8Ci,9Ci)
CAS No.	28860-76-6
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	9-Bicyclo[6.1.0]non-2-ene-9-carbonyl chloride; Bicyclo[6.1.0]non-2-ene-9-carbonyl chloride; (1R,8S)-Bicyclo[6.1.0]non-2-ene-9-carbonyl chloride; (1S,8R)-Bicyclo[6.1.0]non-2-ene-9-carbonyl chloride; 9-Norbornenecarbonyl chloride, 1,2,3,4,5,6,7,8-octahydro-; 1,2,3,4,5,6,7,8-Octahydro-9-norbornenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Bicyclo[6.1.0]Non-2-Ene-9-Carbonyl Chloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as identity, assay, and impurity profile. We adhere to relevant industry standards and can support development projects requiring material for GLP or GMP regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, it should be kept away from moisture, heat, and incompatible materials such as bases, alcohols, and amines. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.