Description

5α-Cholestane-1α,19-Diol is a high-purity steroidal diol derivative, serving as a critical intermediate and reference standard in advanced chemical synthesis and analytical research. Its defined stereochemistry and purity are essential for ensuring the accuracy and reproducibility of experimental results in complex organic pathways. This compound is primarily utilized by research institutions and pharmaceutical developers working on steroid chemistry, metabolic studies, and the development of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex steroid-based active pharmaceutical ingredients (APIs) and novel drug candidates.
• Analytical Reference Standard: Used for method development, calibration, and quality control in chromatographic analyses (HPLC, GC) within pharmaceutical and research laboratories.
• Biochemical Research: Employed in metabolic pathway studies, enzyme inhibition assays, and as a probe for investigating sterol biosynthesis and related biological mechanisms.
• Organic Synthesis: Serves as a versatile chiral starting material or intermediate for the preparation of more complex, functionalized steroidal compounds with specific biological activities.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic chemistry, stereochemistry, and natural product synthesis.

Basic Information

Product Name	5α-Cholestane-1α,19-Diol
CAS No.	28809-55-4
Molecular Formula	C27H48O2
Molecular Weight	404.67 g/mol
Synonyms	1α,19-Dihydroxy-5α-cholestane; 5α-Cholestane-1α,19-diol; (1α,5α,19ξ)-Cholestane-1,19-diol; 1α,19-Dihydroxycholestane; 19-Hydroxy-1α-cholestanol; Steroidal diol intermediate
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-1α,19-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.