Description

5α-Cholestane-2α,19-Diol is a high-purity steroidal diol derivative, serving as a critical intermediate and reference standard in advanced organic synthesis and analytical research. Its defined stereochemistry and functional groups make it a valuable building block for developing novel pharmaceutical compounds and biochemical probes. This compound is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on steroid chemistry and metabolic pathway studies.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of steroidal drugs and hormone analogs.
• Biochemical Research: Used as a standard or precursor in studies of cholesterol metabolism, membrane biology, and lipid signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical and academic laboratories.
• Organic Synthesis: A versatile starting material for the synthesis of complex natural products and specialized steroidal compounds with modified biological activity.
• Metabolite Studies: Employed in metabolic research to investigate enzymatic transformations and catabolic pathways of sterols.

Basic Information

Product Name	5α-Cholestane-2α,19-Diol
CAS No.	28809-54-3
Molecular Formula	C27H48O2
Molecular Weight	404.67 g/mol
Synonyms	2α,19-Dihydroxy-5α-cholestane; 5α-Cholestane-2α,19-diol; (2α,5α)-Cholestane-2,19-diol; 19-Hydroxy-5α-cholestan-2α-ol; Stigmastane-2α,19-diol derivative
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-2α,19-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when appropriate.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.