Description

18,20-Epoxy-5α-Pregnane-3β,14β,20-Triol is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical research and development. This compound is valued for its specific structural framework, which is crucial for the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of specialized steroid-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or precursor in studies investigating steroid hormone pathways, receptor binding, and enzyme inhibition.
• Process Development: Serves as a key material for optimizing and scaling up synthetic routes in pilot plant and commercial manufacturing settings.
• Academic Research: Employed in university and institutional laboratories for fundamental organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	18,20-Epoxy-5α-Pregnane-3β,14β,20-Triol
CAS No.	28708-12-5
Molecular Formula	C21H34O4
Molecular Weight	350.49 g/mol
Synonyms	18,20-Epoxy-5α-pregnane-3β,14β,20-triol; 3β,14β,20-Trihydroxy-18,20-epoxy-5α-pregnane; 18β,20-Epoxy-5α-pregnane-3β,14β,20-triol; 18,20α-Epoxy-5α-pregnane-3β,14β,20-triol; 18,20-Epoxypregnane-3,14,20-triol; Pregnane-3,14,20-triol, 18,20-epoxy-; (3β,5α,14β)-18,20-Epoxy-5-pregnane-3,14,20-triol
EINECS	Contact for details

Quality Control

Our 18,20-Epoxy-5α-Pregnane-3β,14β,20-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.