Description

5-Bromo-2',3'-Dideoxyuridine is a halogenated nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a critical building block and a potent antiviral agent, particularly in the study of viral replication mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, molecular biology, and nucleotide chemistry. The high purity and consistent quality of our product ensure reliable performance in sensitive experimental applications.

Application

• Antiviral Research: Acts as a key intermediate in the synthesis and study of nucleoside-based antiviral agents, particularly against retroviruses.
• Biochemical Probe: Used to investigate DNA/RNA synthesis inhibition and the mechanisms of viral reverse transcriptase enzymes.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the development and manufacturing of novel therapeutic compounds.
• Molecular Biology Studies: Employed in research focused on nucleotide metabolism, mutagenesis, and the function of modified nucleosides.
• Academic & Industrial R&D: A standard reagent for universities and biotech companies conducting foundational life science research.

Basic Information

Product Name	5-Bromo-2',3'-Dideoxyuridine
CAS No.	28616-93-5
Molecular Formula	C9H11BrN2O4
Molecular Weight	291.10 g/mol
Synonyms	5-Bromo-2',3'-dideoxyuridine; 5-Br-ddU; 5-Bromo-ddU; 1-((2R,5S)-5-(Bromomethyl)tetrahydrofuran-2-yl)-5-bromopyrimidine-2,4(1H,3H)-dione; 5-Bromo-1-[(2R,5S)-5-(bromomethyl)oxolan-2-yl]pyrimidine-2,4-dione; BrdUrd (ambiguous, context-specific); 5-Bromo-2',3'-dideoxyuridine (BrdUdd); 5-Bromodideoxyuridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2',3'-Dideoxyuridine is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current industry best practices, and specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.