Description

5-Hydroxymethyl-Arauridine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or building block in the synthesis of novel therapeutic agents, particularly in the antiviral and anticancer domains. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used in studies investigating nucleoside metabolism, enzyme inhibition, and the mechanism of action of therapeutic agents.
• Antiviral Agent Development: Serves as a precursor in the research and development of potential therapeutics targeting viral polymerases.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for synthetic organic chemistry projects and biological activity screening.
• Prodrug Synthesis: Acts as a starting material for creating prodrug forms aimed at improving bioavailability and pharmacokinetic profiles.

Basic Information

Product Name	5-Hydroxymethyl-Arauridine
CAS No.	28608-82-4
Molecular Formula	C10H12N2O6
Molecular Weight	256.21 g/mol
Synonyms	5-(Hydroxymethyl)arauridine; 1-β-D-Arabinofuranosyl-5-(hydroxymethyl)uracil; 5-Hydroxymethyl-1-β-D-arabinofuranosyluracil; Arauridine, 5-hydroxymethyl-; 5-HMAU; 5-Hydroxymethyl-ara-U
EINECS	Contact for details

Quality Control

Our 5-Hydroxymethyl-Arauridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.