Description

3-Oxetanecarbonyl Chloride, 3-Ethyl- (8Ci) is a highly reactive, functionalized oxetane derivative that serves as a versatile building block in advanced organic synthesis. Its value lies in the strained oxetane ring, which imparts unique physicochemical properties and can be used to modulate the metabolic stability and solubility of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating specialized polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly where the oxetane moiety is used as a bioisostere or to improve pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Polymer Chemistry: Monomer for the production of specialized polymers with tailored thermal, mechanical, or optical properties.
• Ligand and Catalyst Development: Precursor for creating complex ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced materials, including liquid crystals and photoactive compounds.
• Cross-coupling Reactions: The acid chloride functionality makes it a suitable substrate for various palladium-catalyzed and other metal-mediated coupling reactions.

Basic Information

Product Name	3-Oxetanecarbonyl Chloride, 3-Ethyl- (8Ci)
CAS No.	28562-62-1
Molecular Formula	C6H9ClO2
Molecular Weight	148.59 g/mol
Synonyms	3-Ethyl-3-oxetanecarbonyl chloride; 3-Ethyloxetane-3-carbonyl chloride; 3-Oxetanecarbonyl chloride, 3-ethyl-; 3-Ethyloxetane-3-carboxylic acid chloride; Oxetane-3-carbonyl chloride, 3-ethyl-; 3-Carboxy-3-ethyloxetane chloride; 3-Ethyl-3-carboxyoxetane chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Oxetanecarbonyl Chloride, 3-Ethyl- is produced and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by GC/HPLC), identity (IR, NMR), and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its properties as a strong acid/organic solvent, hygroscopic (moisture-sensitive), and highly volatile nature, it must be handled under an inert atmosphere (e.g., nitrogen or argon) in a controlled environment and kept away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.