Description

1H-Pyrrole-2-Carbonyl Chloride, 4-Nitro- (9Ci) is a high-purity, reactive chemical intermediate characterized by its nitro-substituted pyrrole backbone and acid chloride functionality. This compound matters for its role as a critical building block in the synthesis of complex heterocyclic molecules, enabling the introduction of the 4-nitropyrrole moiety into target structures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by specialty chemical manufacturers developing advanced materials and dyes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides with specific modes of action.
• Material Science Research: Used in the creation of functional polymers and organic electronic materials due to its electron-withdrawing nitro group.
• Dye and Pigment Manufacturing: Serves as an intermediate for producing specialized heterocyclic dyes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in academic and CRO laboratories.

Basic Information

Product Name	1H-Pyrrole-2-Carbonyl Chloride, 4-Nitro- (9Ci)
CAS No.	28494-49-7
Molecular Formula	C5H3ClN2O3
Molecular Weight	174.54 g/mol
Synonyms	4-Nitro-1H-pyrrole-2-carbonyl chloride; 4-Nitropyrrole-2-carboxylic acid chloride; 2-Pyrrolecarbonyl chloride, 4-nitro-; 4-Nitro-2-pyrrolecarbonyl chloride; 4-Nitro-1H-pyrrole-2-carboxylic acid chloride; 4-Nitropyrrole-2-carbonyl chloride; 1H-Pyrrole-2-carbonyl chloride, 4-nitro-
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2-Carbonyl Chloride, 4-Nitro- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.