Description

(17Z)-11Beta,21-Dihydroxypregna-1,4,17(20)-Trien-3-One 21-Acetate is a high-purity steroid derivative and a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its specific stereochemistry and functional groups, which make it a crucial building block for synthesizing more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within the fields of endocrinology and anti-inflammatory drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates targeting hormone receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid metabolism, enzyme inhibition, and molecular pathways.

Basic Information

Product Name	(17Z)-11Beta,21-Dihydroxypregna-1,4,17(20)-Trien-3-One 21-Acetate
CAS No.	28449-43-6
Molecular Formula	C23H30O5
Molecular Weight	386.49 g/mol
Synonyms	11β,21-Dihydroxypregna-1,4,17(20),Z-trien-3-one 21-acetate; 11β,21-Dihydroxy-17(20)Z-pregna-1,4-dien-3-one 21-acetate; 21-Acetoxy-11β-hydroxypregna-1,4,17(20)Z-trien-3-one; (17Z)-11β,21-Dihydroxypregna-1,4,17(20)-trien-3-one 21-acetate; 11β-Hydroxy-21-acetoxypregna-1,4,17(20)Z-trien-3-one; Pregna-1,4,17(20)Z-trien-3-one, 11β,21-dihydroxy-, 21-acetate
EINECS	Contact for details

Quality Control

Our (17Z)-11Beta,21-Dihydroxypregna-1,4,17(20)-Trien-3-One 21-Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.