Description

3-(2-Thienyl)Acryloyl Chloride is a versatile and highly reactive acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the 3-(2-thienyl)acryloyl moiety into target molecules, enabling the creation of complex structures with tailored properties. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the thiophene ring can contribute to biological activity and photostability.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers, coatings, and advanced materials with specific electronic or mechanical properties.
• Ligand & Catalyst Development: Employed in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs), leveraging the coordinating potential of the sulfur atom.
• Chemical Research & Development: Fundamental reagent for academic and industrial R&D in heterocyclic and medicinal chemistry for exploring new synthetic pathways.
• Dye & Pigment Manufacturing: Intermediate in the synthesis of organic dyes and pigments, where the conjugated system can influence color and lightfastness.

Basic Information

Product Name	3-(2-Thienyl)Acryloyl Chloride
CAS No.	28424-61-5
Molecular Formula	C7H5ClOS
Molecular Weight	172.63 g/mol
Synonyms	3-(2-Thienyl)propenoyl chloride; 3-(Thiophen-2-yl)acryloyl chloride; 2-Thiopheneacryloyl chloride; (E)-3-(Thiophen-2-yl)acryloyl chloride; 3-(2-Thienyl)-2-propenoyl chloride; Thiophene-2-acrylic acid chloride; 2-Thenoic acid, 3-propenoyl chloride; 3-(2-Thienyl)acrylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Thienyl)Acryloyl Chloride undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive synthetic applications. Our quality assurance protocol includes identity confirmation by FT-IR and NMR, purity assessment by HPLC or GC, and control of key impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive and strong acid/organic solvent nature. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.