Description

(22S,23R,25R)-5α-Spirostane-2α,3β,23-Triol is a high-purity, stereochemically defined spirostane derivative. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development, particularly for the synthesis of novel steroidal drugs and bioactive molecules. It is essential for R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors requiring precise, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex steroidal pharmaceuticals and potential therapeutic agents.
• Reference Standard: Used as an analytical standard in quality control (QC) and research laboratories for method development and compound identification.
• Biochemical Research: Employed in studies investigating sterol biosynthesis, enzyme inhibition, and structure-activity relationships (SAR) of steroid-like molecules.
• Fine Chemical Synthesis: A versatile starting material for the custom synthesis of specialized steroidal compounds for various industrial and research applications.
• Academic Research: Utilized in university and institutional labs for organic chemistry research and the development of new synthetic methodologies.

Basic Information

Product Name	(22S,23R,25R)-5α-Spirostane-2α,3β,23-Triol
CAS No.	28415-10-3
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	5α-Spirostane-2α,3β,23-triol, (22S,23R,25R)-; 2α,3β,23-Trihydroxy-5α-spirostan; (22S,23R,25R)-2α,3β,23-Trihydroxyspirostan-5α; 23-Hydroxydiosgenin derivative; Spirostanetriol; Diosgenin triol derivative; 5α-Spirostan-2α,3β,23-triol
EINECS	Contact for details

Quality Control

Our (22S,23R,25R)-5α-Spirostane-2α,3β,23-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical confirmation, and identity verification (IR, NMR). A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.