Description

(22S,23S,25R)-5α-Spirostane-2α,3β,23-Triol is a high-purity, steroidal sapogenin derivative characterized by its specific stereochemistry at the 22, 23, and 25 positions. This compound serves as a critical advanced intermediate and reference standard in the synthesis of complex bioactive molecules, particularly within the pharmaceutical and research sectors. It is essential for organizations engaged in the development of steroid-based therapeutics, natural product chemistry, and biochemical research, where precise molecular structure and high purity are non-negotiable requirements.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based drugs and hormone analogs.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related steroidal compounds.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding activities.
• Natural Product Synthesis: Serves as a starting material or intermediate in the total or semi-synthesis of complex natural products with spirostane skeletons.
• Academic & R&D: Utilized in university and institutional research for exploring new chemical entities and their biological properties.

Basic Information

Product Name	(22S,23S,25R)-5α-Spirostane-2α,3β,23-Triol
CAS No.	28415-09-0
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	5α-Spirostane-2α,3β,23-triol, (22S,23S,25R)-; 2α,3β,23-Trihydroxy-5α-spirostan; (22S,23S,25R)-2α,3β,23-Trihydroxyspirostan-5α; Tigogenin triol derivative; Spirostanetriol
EINECS	Contact for details

Quality Control

Every batch of (22S,23S,25R)-5α-Spirostane-2α,3β,23-Triol is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.