Description

(22S,23S,25R)-3β,23-Dihydroxy-5α-Spirostane is a high-purity, stereochemically defined spirostane derivative, a crucial intermediate in the synthesis of complex steroidal compounds. Its precise stereochemistry is essential for ensuring the biological activity and consistency of downstream pharmaceutical products. This compound is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic agents and plant growth regulators.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of steroidal drugs, including certain classes of hormones, anti-inflammatory agents, and cardiac glycosides.
• Biochemical Research: Used as a reference standard or precursor in studies investigating sterol biosynthesis, enzyme inhibition, and structure-activity relationships (SAR).
• Agrochemical Development: Serves as a starting material for creating novel plant growth regulators and eco-friendly pesticides with specific modes of action.
• Cosmetic Ingredient Synthesis: Potential intermediate for producing specialized sterol-based compounds used in high-end skincare formulations.
• Academic & Process Chemistry: Employed in methodological development for asymmetric synthesis and stereoselective transformations.

Basic Information

Product Name	(22S,23S,25R)-3β,23-Dihydroxy-5α-Spirostane
CAS No.	28415-07-8
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	3β,23-Dihydroxy-5α-spirostane; (22S,23S,25R)-Spirostane-3β,23-diol; 5α-Spirostane-3β,23-diol; 23-Hydroxydiosgenin derivative; Diosgenin diol isomer; Spirostan-3β,23-diol; 3β,23-Dihydroxyspirostan-5α-yl
EINECS	Contact for details

Quality Control

Every batch of (22S,23S,25R)-3β,23-Dihydroxy-5α-Spirostane is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC-MS, and NMR, to verify identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.