Description

2-Methylamino-N6-Methyladenosine is a chemically modified nucleoside derivative of adenosine, featuring methylation at both the exocyclic amine and the 2'-hydroxyl positions. This specific modification is of significant interest in biochemical research and pharmaceutical development for studying RNA structure, function, and epigenetic regulation. It serves as a critical intermediate and reference standard for scientists in the fields of nucleoside chemistry, molecular biology, and medicinal chemistry.

Application

• Biochemical Research: Used as a reference standard and building block in the study of RNA modification, structure, and function.
• Medicinal Chemistry: Serves as a key intermediate in the synthesis of novel nucleoside analogs for potential therapeutic applications.
• Enzyme Substrate Studies: Employed in assays to investigate the activity and specificity of methyltransferase enzymes.
• Epigenetics Research: A valuable tool for exploring the role of RNA methylation in gene expression and cellular processes.
• Pharmaceutical Development: Acts as a precursor in the development of targeted therapies, including potential antiviral or anticancer agents.
• Analytical Standard: Provides a high-purity standard for HPLC, LC-MS, and NMR analysis in quality control and method development.

Basic Information

Product Name	2-Methylamino-N6-Methyladenosine
CAS No.	28360-91-0
Molecular Formula	C₁₂H₁₈N₆O₄
Molecular Weight	310.31 g/mol
Synonyms	N6,2'-O-Dimethyladenosine; 2'-O-Methyl-N6-methyladenosine; 2'-O-Methyl-6-methylaminoadenosine; 6-(Methylamino)-2'-O-methyladenosine; 2'-O-Methyl-N(6)-methyladenosine; N(6)-Methyl-2'-O-methyladenosine; 2-Methylamino-N6-Methyladenosine; 2'-O-Methyl-6-(methylamino)purine riboside
EINECS	Contact for details

Quality Control

Our 2-Methylamino-N6-Methyladenosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.