Description

3α-Fluoroandrost-5-Ene-17β,19-Diol Diacetate is a high-purity, fluorinated steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of specialized steroid-based molecules.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel fluorinated steroid hormones and related bioactive molecules.
• Research Chemical: Used in academic and industrial laboratories to study structure-activity relationships (SAR) of steroid derivatives.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Precursor for Drug Discovery: Employed in medicinal chemistry programs targeting receptors for androgens, estrogens, and other nuclear hormone pathways.
• Biochemical Tool: Utilized in metabolic studies to investigate enzyme inhibition or modulation pathways involving steroid backbones.

Basic Information

Product Name	3α-Fluoroandrost-5-Ene-17β,19-Diol Diacetate
CAS No.	28344-48-1
Molecular Formula	C23H33FO4
Molecular Weight	392.51 g/mol
Synonyms	3α-Fluoro-5-androstene-17β,19-diol 17,19-diacetate; 3α-Fluoroandrost-5-ene-3β,17β-diol 17,19-diacetate; 19-Acetoxy-3α-fluoroandrost-5-en-17β-yl acetate; 3α-Fluoro-19-acetoxyandrost-5-en-17β-yl acetate; Androst-5-ene-17β,19-diol, 3α-fluoro-, 17,19-diacetate; 3α-Fluoroandrost-5-ene-17β,19-diol diacetate; 28344-48-1
EINECS	Contact for details

Quality Control

Every batch of 3α-Fluoroandrost-5-Ene-17β,19-Diol Diacetate is manufactured and tested under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your research or production requirements. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent oxidation. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.