Description

(9S,14S)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-2,3,4,5,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthrene CAS NO 28338-70-7 is a high-purity, stereochemically defined steroid derivative, serving as a critical advanced intermediate in complex organic synthesis. Its precise chiral structure makes it an invaluable building block for pharmaceutical research and development, particularly in the creation of novel therapeutic agents. This compound is essential for R&D chemists and process development scientists working in steroid chemistry, medicinal chemistry, and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the multi-step synthesis of bioactive steroid-based drugs and hormone analogs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in steroid analysis.
• Academic & Industrial R&D: Employed in exploratory synthetic chemistry for constructing complex polycyclic systems and studying stereoselective reactions.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for complex organic molecules requiring specific stereochemistry.

Basic Information

Item	Details
Product Name	(9S,14S)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-2,3,4,5,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthrene
CAS No.	28338-70-7
Molecular Formula	C27H44
Molecular Weight	368.64 g/mol
Synonyms	5β-Cholestane; 5β-Cholestane (8CI); Cholestane, 5β- (6CI); 5β-Cholestane; Allocholestane; Coprostane; NSC 9257; trans-Hexahydrochrysene
EINECS	Contact for details

Quality Control

Our (9S,14S)-10,13-Dimethyl-17-[(2R)-6-Methylheptan-2-Yl]-2,3,4,5,8,9,11,12,14,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthrene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and chiral analysis, to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.