Description

1H-Azepine-1-Carbonyl Chloride, 7-Chloro-2,3,4,5-Tetrahydro-3-Methyl- (8Ci) is a specialized heterocyclic building block and key synthetic intermediate. This compound matters for its role as a reactive acyl chloride derivative, enabling the efficient introduction of the azepine scaffold into more complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for biological activity.
• Organic Synthesis Reagent: Serves as a versatile reagent for amide bond formation and the construction of complex nitrogen-containing heterocycles in academic and industrial R&D.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and functional materials with specific chemical properties.
• Chemical Biology Probe Development: Employed to create molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1H-Azepine-1-Carbonyl Chloride, 7-Chloro-2,3,4,5-Tetrahydro-3-Methyl- (8Ci)
CAS No.	28288-15-5
Molecular Formula	C8H11Cl2NO
Molecular Weight	208.09 g/mol
Synonyms	7-Chloro-3-methyl-2,3,4,5-tetrahydro-1H-azepine-1-carbonyl chloride; 3-Methyl-7-chloro-2,3,4,5-tetrahydro-1H-azepine-1-carbonyl chloride; 1-Carbonylchloride-7-chloro-3-methyl-2,3,4,5-tetrahydro-1H-azepine; 7-Chloro-3-methylperhydroazepine-1-carbonyl chloride; Azepine-1-carbonyl chloride, 7-chloro-2,3,4,5-tetrahydro-3-methyl-; 28288-15-5; 7-Chloro-3-methyl-2,3,4,5-tetrahydro-1H-azepine-1-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency for every batch. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.