Description

5'-(6-Amino-9H-Purin-9-Yl)-5'-Deoxythymidine is a high-purity nucleoside analog, a key building block in pharmaceutical research and development. This compound is critical for the synthesis of novel antiviral and anticancer agents, offering researchers a reliable and consistent starting material. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of nucleoside-based antiviral drugs.
• Anticancer Agent Research: Used in the development and screening of potential chemotherapeutic compounds targeting DNA synthesis.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies related to DNA polymerases and kinases.
• Pro-drug Synthesis: Utilized for creating more bioavailable or targeted forms of active pharmaceutical ingredients (APIs).
• Labeled Compound Production: A starting point for synthesizing isotopically labeled (e.g., C13, N15) compounds for metabolic and pharmacokinetic studies.
• Oligonucleotide Synthesis: Can be incorporated into modified oligonucleotides for antisense or siRNA therapeutic applications.

Basic Information

Product Name	5'-(6-Amino-9H-Purin-9-Yl)-5'-Deoxythymidine
CAS No.	28220-19-1
Molecular Formula	C15H17N7O5
Molecular Weight	375.34 g/mol
Synonyms	5'-Deoxythymidin-5'-yl-6-aminopurine; 5'-(6-Aminopurin-9-yl)-5'-deoxythymidine; 6-Amino-9-(5-deoxy-β-D-threo-pent-4-enofuranosyl)purine; 5'-Deoxy-5'-(6-aminopurin-9-yl)thymidine; dT-6-Aminopurine Conjugate; Nucleoside Analog 28220-19-1
EINECS	Contact for details

Quality Control

Our 5'-(6-Amino-9H-Purin-9-Yl)-5'-Deoxythymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.