Description

17B-Hydroxy-5A-Androstano[3,2-C]Pyrazole is a high-purity synthetic steroid derivative, specifically a pyrazole-fused androstane, serving as a critical advanced intermediate in pharmaceutical research and development. Its unique fused heterocyclic structure makes it a valuable scaffold for creating novel therapeutic agents targeting hormone-related pathways. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on developing next-generation steroid-based treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs with potential anti-inflammatory, anti-androgenic, or anabolic properties.
• Research Chemical: Used in academic and industrial R&D for studying steroid receptor (e.g., androgen, progesterone) interactions and signal transduction mechanisms.
• Biochemical Tool Compound: Employed in assay development and high-throughput screening to identify and characterize new therapeutic targets within endocrine systems.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical laboratories.
• Precursor for Labeled Compounds: Used in the synthesis of deuterated or radiolabeled (e.g., C-14, H-3) analogs for metabolic and pharmacokinetic studies (ADME).

Basic Information

Product Name	17B-Hydroxy-5A-Androstano[3,2-C]Pyrazole
CAS No.	28032-00-0
Molecular Formula	C21H32N2O
Molecular Weight	328.50 g/mol
Synonyms	17β-Hydroxy-5α-androstano[3,2-c]pyrazole; 5α-Androstano[3,2-c]pyrazol-17β-ol; Androstano[3,2-c]pyrazol-17-ol, (5α,17β)-; 17β-Hydroxy-5α-androstano(3,2-c)pyrazole; 28032-00-0; (5α,17β)-17-Hydroxyandrostano[3,2-c]pyrazole
EINECS	Contact for details

Quality Control

Every batch of 17B-Hydroxy-5A-Androstano[3,2-C]Pyrazole is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including HPLC chromatograms and full spectral data (NMR, MS). Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.