Description

4,5-Dichlorothiophene-2-Carbonyl Chloride is a high-value, reactive organosulfur building block used in advanced organic synthesis. This compound is critical for the development of novel heterocyclic compounds, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and specialty chemical intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel thiophene-based drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with thiophene cores.
• Material Science Research: Used in the creation of functionalized monomers for conductive polymers and organic electronic materials.
• Dye & Pigment Industry: Intermediate for synthesizing specialized heterocyclic dyes and pigments.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for bespoke chemical synthesis services for research and pilot-scale production.

Basic Information

Product Name	4,5-Dichlorothiophene-2-Carbonyl Chloride
CAS No.	28025-61-8
Molecular Formula	C5HCl3OS
Molecular Weight	211.48 g/mol
Synonyms	2,3-Dichlorothiophene-5-carbonyl chloride; 2,3-Dichloro-5-thiophenecarbonyl chloride; 5-Chlorocarbonyl-2,3-dichlorothiophene; 2,3-Dichlorothiophene-5-carboxylic acid chloride; 2,3-Dichloro-5-carboxythiophene chloride
EINECS	Contact for details

Quality Control

Our 4,5-Dichlorothiophene-2-Carbonyl Chloride is manufactured under strict quality control protocols. Each batch is analyzed to ensure high chemical purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.