Description

Uracil, 5-β-D-Ribofuranosyl-, 5'-(Tetrahydrogen Triphosphate), Tetrasodium Salt (8Ci) is a high-purity nucleotide derivative, specifically the tetrasodium salt of 5-uridine triphosphate (UTP). This compound serves as a critical building block and energy source in enzymatic and biochemical synthesis processes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and molecular diagnostics sectors, particularly for applications involving RNA synthesis, enzymatic assays, and metabolic studies.

Application

• Substrate for RNA Polymerases: Used as a direct nucleotide precursor in in vitro transcription for mRNA, siRNA, and other RNA molecule synthesis.
• Enzymatic Assays & Diagnostics: Acts as a co-substrate or energy donor in kinase, synthase, and other enzyme-coupled assays for drug discovery and clinical diagnostics.
• Biochemical Research: Employed in studies of cellular metabolism, nucleotide salvage pathways, and glycosylation processes.
• Pharmaceutical Intermediate: Serves as a key starting material in the synthesis of nucleotide-based prodrugs and antiviral agents.
• Cell Culture & Media Supplement: Can be used in specialized cell culture media to support metabolic functions in certain cell lines.

Basic Information

Product Name	Uracil, 5-β-D-Ribofuranosyl-, 5'-(Tetrahydrogen Triphosphate), Tetrasodium Salt (8Ci)
CAS No.	28022-82-4
Molecular Formula	C9H11N2O15P3Na4
Molecular Weight	586.10 g/mol (anhydrous basis)
Synonyms	Uridine 5'-triphosphate tetrasodium salt; UTP tetrasodium salt; 5'-UTP Na4; Uridine-5'-triphosphoric acid tetrasodium salt; Uridine triphosphate tetrasodium salt; UTP Na4; 5-Uridylic acid triphosphate tetrasodium salt
EINECS	Contact for details

Quality Control

Our nucleotide products are manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research and production applications. Each lot is tested for identity, purity, and the absence of critical impurities such as nucleases. Certificates of Analysis (COA) detailing specifications including assay (by HPLC), pH, endotoxin levels, and bioburden are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Assay (HPLC)	≥95%
pH (1% Solution)	7.0 - 9.0
Water Content (KF)	≤5.0%
Endotoxin	<10 EU/mg
Bioburden	<100 CFU/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.