Description

(14β,17α)-3β,19-Diacetoxy-5,14-Dihydroxy-21-(Chloroacetoxy)-5β-Pregnan-20-One is a high-purity, multi-functional steroid derivative with a complex molecular structure. This compound serves as a critical advanced intermediate in the synthesis of specialized pharmaceutical agents, particularly in the development of corticosteroids and other bioactive steroids. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in steroid chemistry and novel drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potent corticosteroid APIs and other therapeutic steroid molecules.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, receptor binding, and structure-activity relationships (SAR).
• Process Chemistry: Employed in the development and scale-up of synthetic routes for complex steroid-based pharmaceuticals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Tool: Utilized in biochemical assays to investigate enzyme inhibition or modulation related to steroid pathways.

Basic Information

Product Name	(14β,17α)-3β,19-Diacetoxy-5,14-Dihydroxy-21-(Chloroacetoxy)-5β-Pregnan-20-One
CAS No.	28008-41-5
Molecular Formula	C₂₈H₃₉ClO₉
Molecular Weight	555.06 g/mol
Synonyms	21-Chloroacetoxy-3β,19-diacetoxy-5β,14β,17α-trihydroxypregnan-20-one; 5β-Pregnan-20-one, 3β,19-diacetoxy-5,14-dihydroxy-21-(chloroacetoxy)-, (3β,5β,14β,17α)-; 3β,19-Diacetoxy-5,14-dihydroxy-21-chloroacetoxy-5β-pregnan-20-one; 21-Chloroacetoxy-3β,19-diacetoxy-5β,14β,17α-trihydroxy-pregnan-20-one; 5β,14β,17α-Trihydroxy-3β,19-diacetoxy-21-chloroacetoxypregnan-20-one
EINECS	Contact for details

Quality Control

Our (14β,17α)-3β,19-Diacetoxy-5,14-Dihydroxy-21-(Chloroacetoxy)-5β-Pregnan-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via spectroscopic methods (IR, NMR), and specific tests for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.