Description

7-Methyl-8-Oxoguanosine is a chemically modified nucleoside derivative of guanosine, characterized by specific methylation and oxidation at the 7 and 8 positions, respectively. This structural modification makes it a valuable intermediate and reference standard in advanced biochemical and pharmaceutical research. It is primarily utilized by research institutions and companies engaged in nucleoside chemistry, medicinal chemistry, and the development of nucleic acid-based therapeutics. The compound, with CAS number 28007-87-6, is essential for studies involving RNA modification, metabolic pathways, and the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel nucleoside analogs for potential antiviral or anticancer agents.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies to investigate RNA modification processes and repair mechanisms.
• Medicinal Chemistry: Acts as a building block for creating modified oligonucleotides to study structure-activity relationships and enhance therapeutic properties.
• Academic Research: Employed in universities and research institutes for fundamental studies on nucleoside metabolism, oxidative damage, and epigenetic markers.
• Diagnostic Reagent Development: Potential use in developing assays and kits for detecting specific nucleic acid modifications or related enzymatic activities.
• Life Science Tools: Incorporated into proprietary research tools and kits for studying gene expression and cellular signaling pathways.

Basic Information

Item	Detail
Product Name	7-Methyl-8-Oxoguanosine
CAS No.	28007-87-6
Molecular Formula	C11H15N5O6
Molecular Weight	313.27 g/mol
Synonyms	8-Oxo-7-methylguanosine; 7-Methyl-8-oxoguanosine; 7-Methyl-8-oxo-guanosine; 7-Methylguanine-8-one riboside; 7-Methyl-8-hydroxyguanosine (tautomeric form); N7-Methyl-8-oxoguanosine; Guanosine, 7-methyl-8-oxo-; 8-Hydroxy-7-methylguanosine
EINECS	Contact for details

Quality Control

Our 7-Methyl-8-Oxoguanosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality systems are designed to meet the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.