Description

5'-Amino-5'-Deoxythymidine 3'-Acetate is a chemically modified nucleoside derivative, serving as a critical building block in advanced organic synthesis and pharmaceutical research. Its primary value lies in its role as a versatile intermediate for the development of novel antiviral agents, oligonucleotide probes, and modified nucleic acids. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used as a modified monomer for creating labeled probes and functionalized nucleic acid sequences for research and diagnostics.
• Bioconjugation: The amino group provides a handle for attaching fluorescent dyes, affinity tags, or other functional molecules to nucleic acid structures.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Tool Development: Employed in the creation of enzyme inhibitors and molecular tools to study biological pathways involving DNA and RNA.

Basic Information

Product Name	5'-Amino-5'-Deoxythymidine 3'-Acetate
CAS No.	27930-49-0
Molecular Formula	C12H17N3O6
Molecular Weight	299.28 g/mol
Synonyms	3'-O-Acetyl-5'-amino-5'-deoxythymidine; 5'-Amino-2'-deoxy-5'-deoxythymidine 3'-acetate; 5'-Amino-5'-deoxy-3'-O-acetylthymidine; 3'-Acetoxy-5'-aminothymidine; dT(Ac)3'-NH25'; Thymidine, 5'-amino-5'-deoxy-, 3'-acetate; 5'-Amino-5'-deoxythymidine 3'-O-acetate
EINECS	Contact for details

Quality Control

Our 5'-Amino-5'-Deoxythymidine 3'-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.