Description

(20S,25R)-5,6β-Epoxy-4β,22-Dihydroxy-1-Oxo-5β-Ergost-2-En-26-Oic Acid δ-Lactone CAS NO 27868-19-5 is a high-purity, complex ergostane-type steroidal lactone of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules with potential therapeutic applications. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on steroid chemistry, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and bioactive compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related steroidal substances.
• Biochemical Research: Employed in studies investigating enzyme inhibition, receptor binding, and metabolic pathways involving steroidal frameworks.
• Academic Research: Serves as a substrate or model compound in university and institutional research exploring organic synthesis and natural product chemistry.
• Preclinical Development: Utilized in the early-stage discovery and development of new chemical entities (NCEs) for various therapeutic areas.

Basic Information

Item	Details
Product Name	(20S,25R)-5,6β-Epoxy-4β,22-Dihydroxy-1-Oxo-5β-Ergost-2-En-26-Oic Acid δ-Lactone
CAS No.	27868-19-5
Molecular Formula	C28H38O6
Molecular Weight	470.60 g/mol
Synonyms	5,6β-Epoxy-4β,22-dihydroxy-1-oxo-5β-ergost-2-en-26-oic acid δ-lactone; (20S,25R)-Withaferin A Diol Epoxide Lactone; 27868-19-5; Withanolide derivative; Ergostane lactone; 4β,22-Dihydroxy-5,6β-epoxy-1-oxo-5β-ergost-2-en-26-oic acid δ-lactone
EINECS	Contact for details

Quality Control

Our (20S,25R)-5,6β-Epoxy-4β,22-Dihydroxy-1-Oxo-5β-Ergost-2-En-26-Oic Acid δ-Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the product should be handled under an inert atmosphere to prevent oxidation and kept in moisture-free conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.