Description

Gitoxigenin Bisdigitoxoside is a high-purity cardiac glycoside derivative, specifically a bisdigitoxoside of gitoxigenin. This compound serves as a critical reference standard and key intermediate in pharmaceutical research and development, particularly for studies involving cardiac pharmacology. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research laboratories engaged in the synthesis and analysis of heart failure medications.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of cardiac glycoside drugs and their metabolites.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the manufacture of certain cardiac medications.
• Biochemical Research: Employed in studies investigating the mechanism of action of Na+/K+-ATPase inhibition.
• Pharmacological Screening: Used as a standard compound in high-throughput screening assays for cardiac activity.
• Impurity Profiling: Essential for identifying and quantifying related substances in bulk drug substances and finished dosage forms.
• Academic Research: Supports fundamental research in medicinal chemistry and natural product synthesis.

Basic Information

Product Name	Gitoxigenin Bisdigitoxoside
CAS No.	27856-87-7
Molecular Formula	C₄₁H₆₄O₁₃
Molecular Weight	764.94 g/mol
Synonyms	Gitoxin Bisdigitoxoside; 3β-[(2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14,16β-dihydroxy-5β-card-20(22)-enolide; 16β-Hydroxydigitoxin; Gitoxigenin bis-D-digitoxoside; Anhydrogitoxin bisdigitoxoside; Gitoxigenin-3-O-bisdigitoxoside
EINECS	Contact for details

Quality Control

Our Gitoxigenin Bisdigitoxoside is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.