Description

4-Acetamido-4'-Isothiocyanatostilbene-2,2'-Disulfonic Acid is a specialized organic compound featuring a reactive isothiocyanate group and sulfonic acid functionalities. This unique structure makes it a valuable intermediate for the synthesis of fluorescent probes and affinity labels used in biochemical and biophysical research. It is primarily utilized by research institutions, diagnostic manufacturers, and pharmaceutical R&D departments developing advanced analytical and detection methodologies.

Application

• Fluorescent Labeling Reagent: Used to covalently label proteins, antibodies, and other biomolecules via its reactive isothiocyanate group for fluorescence microscopy and flow cytometry.
• Bioconjugation Intermediate: Serves as a key building block in the synthesis of more complex fluorescent dyes and molecular probes.
• Biochemical Research: Employed in studying protein interactions, cellular localization, and receptor-ligand binding due to its derivatization capability.
• Diagnostic Assay Development: Used in the manufacturing of reagents for immunoassays and other clinical diagnostic tests requiring high-sensitivity detection.
• Material Science: Potential application in the development of advanced polymeric materials with specific optical properties.

Basic Information

Product Name	4-Acetamido-4'-Isothiocyanatostilbene-2,2'-Disulfonic Acid
CAS No.	27816-59-7
Molecular Formula	C₁₇H₁₄N₂O₇S₃
Molecular Weight	454.50 g/mol
Synonyms	SITS; 4-Acetamido-4'-isothiocyanato-stilbene-2,2'-disulfonic acid; 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonate; Stilbene isothiocyanate disulfonic acid; SITS disodium salt (common salt form); 4-Acetamido-4'-isothiocyanato-2,2'-stilbenedisulfonic Acid; NSC 403919; 2,2'-(1E)-2-[4-(Acetylamino)phenyl]ethene-1,1-diyl]bis(5-isothiocyanatobenzenesulfonic acid)
EINECS	Contact for details

Quality Control

Our 4-Acetamido-4'-Isothiocyanatostilbene-2,2'-Disulfonic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.