Description

(20R,25R)-5,6β-Epoxy-4β,20,22-Trihydroxy-1-Oxo-5β-Ergost-2-En-26-Oic Acid δ-Lactone is a high-purity, complex steroidal lactone compound of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of bioactive molecules with potential therapeutic applications. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in steroid chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical method development, validation, and quality control (QC) for purity assessment via HPLC, LC-MS, or NMR.
• Biochemical Research: Investigation of steroid biosynthesis pathways, enzyme inhibition studies, and structure-activity relationship (SAR) research.
• Preclinical Studies: Serves as a starting material or metabolite analog in pharmacological and toxicological evaluations.
• Academic Research: Fundamental studies in organic and medicinal chemistry focused on complex natural product synthesis and modification.

Basic Information

Product Name	(20R,25R)-5,6β-Epoxy-4β,20,22-Trihydroxy-1-Oxo-5β-Ergost-2-En-26-Oic Acid δ-Lactone
CAS No.	27806-45-7
Molecular Formula	C₂₈H₄₀O₇
Molecular Weight	488.62 g/mol
Synonyms	5,6β-Epoxy-4β,20,22-trihydroxy-1-oxo-5β-ergost-2-en-26-oic acid δ-lactone; (20R,25R)-Epoxyergostadienolide; 5,6α-Epoxy-4β,20,22-trihydroxy-1-oxoergosta-2,24-dien-26-oic acid δ-lactone; 27806-45-7; A fungal metabolite; An ergostane-type sterol lactone.
EINECS	Contact for details

Quality Control

Our (20R,25R)-5,6β-Epoxy-4β,20,22-Trihydroxy-1-Oxo-5β-Ergost-2-En-26-Oic Acid δ-Lactone is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.