Description

(20R)-Pregna-5-Ene-3β,8,11α,12β,14β,20-Hexol is a high-purity, multi-hydroxylated pregnane derivative, a key intermediate in the synthesis of complex steroid-based pharmaceuticals and research compounds. Its precise stereochemistry and functional group array make it a valuable building block for developing novel therapeutic agents targeting hormonal and metabolic pathways. This compound is essential for R&D and production in the pharmaceutical, biotechnology, and fine chemical sectors, where advanced steroid chemistry is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of specialized corticosteroids, anti-inflammatory agents, and other bioactive steroid molecules.
• Biochemical Research: Used as a reference standard and starting material in metabolic pathway studies, enzyme inhibition assays, and receptor binding research.
• Fine Chemical Synthesis: Serves as a chiral template for constructing complex natural products and novel chemical entities in advanced organic synthesis.
• Academic & Institutional Research: Employed in universities and research institutes for investigating steroid biosynthesis, structure-activity relationships (SAR), and drug discovery projects.

Basic Information

Product Name	(20R)-Pregna-5-Ene-3β,8,11α,12β,14β,20-Hexol
CAS No.	27642-30-4
Molecular Formula	C21H34O6
Molecular Weight	382.49 g/mol
Synonyms	3β,8,11α,12β,14β,20-Hexahydroxypregn-5-ene; 20R-Pregna-5-ene-3β,8,11α,12β,14β,20-hexol; Pregna-5-ene-3β,8,11α,12β,14β,20-hexol, (20R)-; 27642-30-4; 3β,8,11α,12β,14β,20-Hexahydroxy-5-pregnene
EINECS	Contact for details

Quality Control

Our (20R)-Pregna-5-Ene-3β,8,11α,12β,14β,20-Hexol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.