Description

2-Propenoyl Chloride, 3-(4-Bromophenyl)- is a specialized organic building block characterized by its reactive acryloyl chloride moiety and a brominated aromatic ring. This compound is valued for its dual functionality, enabling it to act as a key intermediate in the synthesis of more complex molecules through reactions like nucleophilic substitution and polymerization. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the bromophenyl group contributes to biological activity.
• Polymer Chemistry: Acts as a reactive monomer or cross-linking agent for creating specialty polymers with specific optical, mechanical, or surface properties.
• Liquid Crystal & OLED Materials: Employed in the development of organic electronic materials and display technologies due to its conjugated structure.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis and material science.
• Covalent Organic Framework (COF) Construction: Utilized as a linker molecule in the bottom-up synthesis of porous crystalline materials for gas storage or catalysis.

Basic Information

Item	Detail
Product Name	2-Propenoyl Chloride, 3-(4-Bromophenyl)-
CAS No.	27465-66-3
Molecular Formula	C9H6BrClO
Molecular Weight	245.50 g/mol
Synonyms	3-(4-Bromophenyl)acryloyl chloride; 4-Bromocinnamoyl chloride; (E)-3-(4-Bromophenyl)acryloyl chloride; trans-4-Bromocinnamoyl chloride; p-Bromocinnamoyl chloride; 3-(p-Bromophenyl)-2-propenoyl chloride; (2E)-3-(4-Bromophenyl)prop-2-enoyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Propenoyl Chloride, 3-(4-Bromophenyl)- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analysis, including purity assay and impurity profiling via advanced chromatographic techniques. Certificates of Analysis (COA) documenting identity, purity, and relevant specifications are provided with every shipment. We operate under a quality management system aligned with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	85 - 89 °C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.