Description

9-(β-D-Xylofuranosyl)Guanine is a nucleoside analog with significant biochemical and pharmaceutical research applications. This compound matters as a key intermediate and reference standard in the development of antiviral and anticancer agents, particularly those targeting nucleic acid synthesis. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs) for investigative and process development purposes.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Studies: Used as a reference standard and substrate in enzymatic studies to understand nucleoside metabolism and polymerase inhibition.
• Process Chemistry: Employed as a building block in the scaled-up synthesis of more complex therapeutic candidates under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in medicinal chemistry and molecular biology.
• Quality Control & Analytical Standards: Acts as a high-purity certified reference material (CRM) for analytical method development and validation in QC laboratories.

Basic Information

Product Name	9-(β-D-Xylofuranosyl)Guanine
CAS No.	27462-39-1
Molecular Formula	C10H13N5O5
Molecular Weight	283.24 g/mol
Synonyms	9-β-D-Xylofuranosylguanine; Guanine, 9-β-D-xylofuranosyl-; Xylosylguanine; 9-(β-D-Xylofuranosyl)-2-amino-6-hydroxypurine; 2-Amino-9-β-D-xylofuranosyl-1,9-dihydro-6H-purin-6-one; 9-(β-D-Xylofuranosyl)guanine; NSC 401005
EINECS	Contact for details

Quality Control

Our 9-(β-D-Xylofuranosyl)Guanine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches undergo comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.