Description

Fosfomycin Diastereomer 1 is a specific stereoisomeric form of the broad-spectrum antibiotic fosfomycin. This precise chemical entity is critical for advanced pharmaceutical research and development, particularly in the study of structure-activity relationships, metabolic pathways, and the synthesis of novel antimicrobial agents. It serves as an essential reference standard and building block for scientists and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity, well-characterized compounds for their work.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control testing of fosfomycin-based drugs.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key chiral synthon in the research-scale synthesis of novel antibiotic compounds and prodrugs.
• Metabolic and Pharmacokinetic Studies: Employed in research to investigate the absorption, distribution, metabolism, and excretion (ADME) profiles of different fosfomycin stereoisomers.
• Biochemical Research: Utilized as a tool compound in enzymatic assays and studies targeting bacterial cell wall synthesis pathways.
• Impurity Profiling: Acts as a critical impurity standard to monitor and control the stereochemical purity of bulk fosfomycin APIs during manufacturing.

Basic Information

Product Name	Fosfomycin Diastereomer 1
CAS No.	27357-50-2
Molecular Formula	C3H7O4P
Molecular Weight	138.06 g/mol
Synonyms	(1R,2S)-1,2-Epoxypropylphosphonic Acid; (-)-(1R,2S)-1,2-Epoxypropylphosphonic Acid; Fosfomycin Isomer A; (1R,2S)-Fosfomycin; Fosfomycin cis-Epoxide; Antibiotic MK-955; Phosphomycin Diastereomer 1
EINECS	Contact for details

Quality Control

Our Fosfomycin Diastereomer 1 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (Diastereomer 1)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.