Description

2,3-Dihydro-1-Benzofuran-2-Carbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of the benzofuran scaffold. Its primary value lies in its role as a key building block for synthesizing more complex molecules, enabling the efficient introduction of the 2,3-dihydrobenzofuran moiety into target compounds. This product is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides that incorporate the benzofuran structure for enhanced biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic semiconductors, liquid crystals, and polymers with specific optical or electronic properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling biomolecules or synthesizing activity-based probes for enzyme studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2,3-Dihydro-1-Benzofuran-2-Carbonyl Chloride
CAS No.	27347-32-6
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	2,3-Dihydrobenzofuran-2-carbonyl chloride; 2-(Chlorocarbonyl)-2,3-dihydro-1-benzofuran; 2,3-Dihydro-2-benzofurancarbonyl chloride; 2,3-Dihydrobenzo[b]furan-2-carbonyl chloride; 2-Carboxy-2,3-dihydrobenzofuran chloride; Dihydrobenzofuranyl-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-1-Benzofuran-2-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its reactivity as an acid chloride and sensitivity to moisture, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.