Description

Thevetin CAS NO 27127-79-3 is a cardiac glycoside compound derived from plants of the *Thevetia* genus, known for its potent biological activity. This high-purity chemical is critical for research and development in the pharmaceutical and life sciences sectors, where precise and reliable active ingredients are paramount. It is primarily utilized by researchers, formulation scientists, and manufacturers focused on cardiovascular studies, toxicology, and the development of reference standards.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in cardiovascular drug discovery.
• Biochemical Studies: Used in pharmacological assays to study ion channel function (specifically Na+/K+-ATPase inhibition) and cardiac muscle contractility.
• Toxicology & Safety Assessment: Employed as a calibrated toxin in studies investigating plant poisoning and developing diagnostic or therapeutic countermeasures.
• Analytical Chemistry: Functions as a high-purity standard for qualitative and quantitative analysis (e.g., HPLC, LC-MS) in quality control laboratories.
• Academic Research: Utilized in university and institutional labs for teaching and investigating the mechanisms of cardiac glycosides.

Basic Information

Product Name	Thevetin
CAS No.	27127-79-3
Molecular Formula	C42H66O18
Molecular Weight	858.97 g/mol
Synonyms	Thevetin; Thevetoside; Cerberin; Thevetin A; Thevetin B; 3β-[(O-β-D-Glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide; NSC 89377
EINECS	Contact for details

Quality Control

Our Thevetin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research use. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.