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3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide CAS NO 26931-65-7


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CAS No.:26931-65-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for developing targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel cardiovascular drugs and specialized biochemical research.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
  • Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
  • Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new cardioprotective or inotropic agents.
  • Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.

Basic Information

Product Name 3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide
CAS No. 26931-65-7
Molecular Formula C29H42O9
Molecular Weight 534.64 g/mol
Synonyms 19-Oxocymarin; 19-Oxocinobufagin 3-alloside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14β-hydroxy-19-oxo-5β-card-20(22)-enolide; 3-Allosyl-19-oxocinobufagin; 19-Oxo-3-allosylcinobufagin; Cardiac glycoside derivative 26931-65-7; 3β-[(6-Deoxy-α-L-allopyranosyl)oxy]-14β-hydroxy-19-oxo-5β,14β-card-20(22)-enolide
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Quality Control

Our 3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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