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3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide CAS NO 26931-65-7
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CAS No.:26931-65-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. This compound is valued for its specific stereochemistry and functional groups, which are essential for developing targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel cardiovascular drugs and specialized biochemical research.
Application
- Pharmaceutical Intermediate: A key building block in the synthesis of novel cardiac glycosides and related therapeutic compounds.
- Biochemical Research: Used as a reference standard or probe in studies investigating sodium-potassium ATPase (Na+/K+-ATPase) inhibition and cardiac cell signaling pathways.
- Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies aimed at developing new cardioprotective or inotropic agents.
- Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
Basic Information
| Product Name | 3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide |
| CAS No. | 26931-65-7 |
| Molecular Formula | C29H42O9 |
| Molecular Weight | 534.64 g/mol |
| Synonyms | 19-Oxocymarin; 19-Oxocinobufagin 3-alloside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-14β-hydroxy-19-oxo-5β-card-20(22)-enolide; 3-Allosyl-19-oxocinobufagin; 19-Oxo-3-allosylcinobufagin; Cardiac glycoside derivative 26931-65-7; 3β-[(6-Deoxy-α-L-allopyranosyl)oxy]-14β-hydroxy-19-oxo-5β,14β-card-20(22)-enolide |
| EINECS | Contact for details |
Quality Control
Our 3β-[(6-Deoxy-D-Allopyranosyl)Oxy]-14β-Hydroxy-19-Oxo-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or cGMP guidelines for pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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