Description

2'-Azido-2'-Deoxyuridine is a synthetic nucleoside analog featuring an azido group at the 2' position of the sugar moiety. This compound is a crucial building block and research tool in medicinal chemistry and biochemistry, particularly for the study of nucleoside metabolism and the development of antiviral and anticancer agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in nucleoside-based drug discovery programs.

Application

• Antiviral Research: Serves as a key intermediate in the synthesis and investigation of novel nucleoside analogs targeting viral polymerases.
• Cancer Research: Used in studies exploring the mechanism of action and development of nucleoside-based chemotherapeutic agents.
• Biochemical Probes: Acts as a substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and repair pathways.
• Medicinal Chemistry: A fundamental scaffold for the structural modification and creation of libraries for high-throughput screening in drug discovery.
• Metabolic Studies: Employed to trace and understand the cellular uptake and metabolic fate of modified nucleosides.
• Academic & Industrial R&D: Essential for basic research in molecular biology and for applied research in biotechnology and pharmaceutical development.

Basic Information

Product Name	2'-Azido-2'-Deoxyuridine
CAS No.	26929-65-7
Molecular Formula	C9H11N5O5
Molecular Weight	269.22 g/mol
Synonyms	2'-Azido-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; 2'-N3-2'-dU; Azidodeoxyuridine; 2'-Azido-2'-deoxy-Uridine; 2'-Azido-dU; 2'-N3-2'-deoxyuridine
EINECS	Contact for details

Quality Control

Our 2'-Azido-2'-Deoxyuridine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.