Description

5-Methyl-1-β-L-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione is a specialized nucleoside derivative, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role as a precursor in the synthesis of modified nucleosides and nucleotides, which are critical for developing antiviral agents, anticancer drugs, and molecular probes. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Nucleoside Chemistry: Serves as a key starting material for the chemical modification of ribose or pyrimidine bases to create novel compounds.
• Antiviral Drug Development: Investigated for its potential incorporation into oligonucleotides targeting viral replication.
• Molecular Probe Synthesis: Utilized in creating labeled nucleosides for diagnostic and imaging applications.
• Academic & Industrial R&D: Fundamental material for exploring structure-activity relationships (SAR) in medicinal chemistry projects.

Basic Information

Product Name	5-Methyl-1-β-L-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione
CAS No.	26879-47-0
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	5-Methyluridine; 5-Methyl-1-β-L-ribofuranosyluracil; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methylpyrimidine-2,4-dione; 5-Methyl-L-uridine; Thymine β-L-riboside; L-Thymidine (Note: This is the L-enantiomer of the common D-thymidine); 5-Methyl-Urd
EINECS	Contact for details

Quality Control

Our 5-Methyl-1-β-L-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Optical Rotation	Specific range available on COA
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.