Description

3-(3,4-Dimethyl-Phenyl)-Propionyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value proposition lies in enabling the efficient introduction of the 3,4-dimethylphenylpropionyl moiety, a key structural feature for modulating the physical and biological properties of target molecules. This intermediate is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, where the dimethylphenyl group enhances lipophilicity and bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized organic compounds used in electronic displays and optoelectronic devices.
• Polymer Modification: Employed as a coupling agent or chain extender to introduce aromatic character and modify the properties of engineering plastics and high-performance polymers.
• Peptide & Protein Research: Utilized as an acylating agent in peptide synthesis to modify amino acid side chains or create custom linkers for bioconjugation.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments, contributing to color fastness and stability.

Basic Information

Product Name	3-(3,4-Dimethyl-Phenyl)-Propionyl Chloride
CAS No.	26801-37-6
Molecular Formula	C11H13ClO
Molecular Weight	196.67 g/mol
Synonyms	3,4-Dimethylhydrocinnamoyl chloride; 3-(3,4-Dimethylphenyl)propanoic acid chloride; 3,4-Dimethylphenylpropionyl chloride; β-(3,4-Dimethylphenyl)propionyl chloride; 3,4-Dimethylbenzenepropanoyl chloride; 26801-37-6; 3,4-Xylylpropionyl chloride
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dimethyl-Phenyl)-Propionyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its hygroscopic and moisture-sensitive nature, containers must be kept sealed and allowed to reach ambient temperature before opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.