Description

3α,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide is a high-purity bufadienolide derivative, a class of compounds known for their significant biological activity. This compound serves as a critical advanced pharmaceutical intermediate and a valuable reference standard for research and development. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardioactive drugs and other therapeutic agents.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) in pharmaceutical manufacturing.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of bufadienolides and their mechanisms of action.
• Preclinical Studies: Serves as a starting material or standard in pharmacological and toxicological research.
• Fine Chemical Synthesis: Utilized in the preparation of complex, high-value organic molecules for specialized applications.

Basic Information

Product Name	3α,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide
CAS No.	26611-41-6
Molecular Formula	C₂₄H₃₂O₆
Molecular Weight	416.51 g/mol
Synonyms	19-Oxobufalin; 19-Oxobufa-4,20,22-trienolide-3α,14-diol; 3α,14-Dihydroxy-19-oxobufa-4,20,22-trienolide; 19-Oxo-bufalin; 19-Oxobufa-4,20,22-trienolide, 3α,14-dihydroxy-; Bufadienolide derivative; 19-Ketobufalin
EINECS	Contact for details

Quality Control

Our 3α,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR, MS), to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.