Description

Inosine 5'-(Trihydrogen Diphosphate), 2'-Deoxy- is a high-purity nucleotide derivative, also known as dITP, essential for biochemical research and diagnostic applications. Its primary value lies in its role as a substrate for DNA polymerases, enabling controlled synthesis and sequencing in molecular biology workflows. This compound is critically needed by biotechnology firms, pharmaceutical R&D laboratories, and diagnostic kit manufacturers for applications such as PCR, DNA labeling, and next-generation sequencing.

Application

• Molecular Biology Research: Used as a substrate for DNA polymerases in enzymatic DNA synthesis, PCR, and site-directed mutagenesis.
• Next-Generation Sequencing (NGS): Serves as a key component in sequencing-by-synthesis (SBS) platforms for accurate base incorporation.
• Diagnostic Assay Development: Employed in the formulation of probes and primers for infectious disease and genetic disorder testing kits.
• Biochemical Studies: Utilized to study enzyme kinetics, nucleotide metabolism, and polymerase fidelity mechanisms.
• Pharmaceutical R&D: Acts as a raw material or intermediate in the development of nucleotide-based therapeutics and antiviral agents.

Basic Information

Product Name	Inosine 5'-(Trihydrogen Diphosphate), 2'-Deoxy-
CAS No.	26575-15-5
Molecular Formula	C10H15N4O13P3
Molecular Weight	492.16 g/mol
Synonyms	2'-Deoxyinosine-5'-triphosphate; dITP; Deoxyinosine triphosphate; 2'-Deoxy-ITP; 9-[(2R,3S,5R)-3-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3,9-dihydro-1H-purin-6-one 5'-(trihydrogen diphosphate); Inosine, 2'-deoxy-, 5'-(trihydrogen triphosphate)
EINECS	Contact for details

Quality Control

Our Inosine 5'-(Trihydrogen Diphosphate), 2'-Deoxy- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house specifications, and the product is suitable for use under ISO 9001 quality management guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin	< 10 EU/mg
Biological Activity	Suitable for enzymatic reactions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.